✦ The team you'd be joining
ACRO's biostatistics team designs and executes statistical methodology across clinical trials, observational studies, and real-world evidence research. From Phase I dose decisions through Phase III registrational SAPs to RWE analyses for HIRA and MFDS submissions, one statistician owns a project from start to finish.
We work on the substantial clinical data available through a tertiary academic hospital to drive real change in healthcare — not just adopting new methods, but applying them directly to clinical practice and study protocols to create tangible value. Through collaborative research projects with Boston-cluster partner institutions, we absorb methodology at international standard and adapt it to the Korean clinical environment. That is our team's identity.
Our recent work has expanded around adaptive trial design, Bayesian inference, and target trial emulation–based RWE research, and we are looking for a senior statistician to join us.
✦ What you'd do
- Trial design & SAP development: Lead the statistical design (traditional and adaptive) of Phase I–III trials, sample size calculation, and the writing and validation of Statistical Analysis Plans (SAPs).
- Adaptive trial execution: Conduct simulation and operating-characteristics analyses for Bayesian dose-finding (BLRM, CRM), group-sequential, and basket/platform designs.
- Real-world evidence (RWE) research: Run comparative effectiveness studies, build external control arms, and design target trial emulation using HIRA claims data, EMR data, and the K-CURE platform.
- Regulatory submission support: Contribute to integrated statistical summaries (ISS, ISE) and Module 2.5/2.7 for MFDS/FDA IND, NDA, and BLA submissions.
- Academic publication & methodology research: Support first- and corresponding-author manuscripts from our studies, with the freedom to pursue methodological research (meta-analyses, simulation studies) of your own.
- Mentoring junior statisticians: Contribute to SAP reviews, code reviews, and academic presentation coaching for entry-level and experienced statisticians.
✦ What we offer
- Methodology publication track: We actively encourage first- or corresponding-author publications from your work, with full coverage of conference fees and article processing charges.
- Boston visiting research opportunities: Annual short-term visiting research (2–8 weeks) with Boston-cluster partner institutions.
- Tools & training: Licenses for SAS, R, Stata, EAST, FACTS and other statistical software, plus support for ASA, ENAR, and JSM conference attendance.
- Flexible work: Core-time–based flexible hours, up to two remote days per week, and dedicated analysis focus days.
✦ Who we're looking for
- Master's degree or higher in statistics, biostatistics, epidemiology, or a related field (PhD preferred)
- 5+ years leading statistical analysis in clinical trials or RWE research
- Strong command of SAS and R, with a habit of reproducible, well-documented analysis code
- Hands-on experience with SAP writing, CSR statistical sections, and CDISC ADaM standards
- Deep expertise in one or more of: adaptive design, Bayesian methods, survival analysis, or causal inference
- Publication experience as first or corresponding author in peer-reviewed journals (preferred)
- Ability to write protocols, SAPs, and manuscripts in English
- A desire to contribute to junior statisticians' growth and the team's overall methodological standards
✦ Hiring process
- Application review: Submit resume, CV, and one representative publication (or analysis report sample)
- First interview: Technical interview with the statistics team lead and two senior statisticians (~90 min)
- Take-home exercise: SAP writing or code review task (feedback within one week of submission)
- Second interview: Leadership and medical advisory interview (~60 min)
- Offer & onboarding